Rebellious Cyclops is a boss found on the 8th floor of Empyrean, accompanied by two Acheron Seekers. It impedes the party's progress and must be beaten to proceed.
Due to the battle's circumstances, only Fire and Elec attacks can do consistent damage to the boss. Physical attacks are not recommended due to the Cyclops' Evade Phys and High Counter, as well as the Seekers' resistance to physical skills. Akihiko, Ken, and Koromaru are the best party members who can hit with Fire and Elec attacks backed by a reasonable Magic stat, while also bringing to the table Masukukaja and Masukunda to offset the Evade skills that the collective bosses will be touting.
Rebellious Cyclops appears on Paths 6 and 7 of Yomotsu Hirasaka within the Midnight Channel. After being defeated, it may drop a Bloody Thorn. Selling 10 Bloody Thorns at the TV extension of Daidara will unlock The Ripper for Teddie.
Persona Q2: New Cinema Labyrinth
Rebellious Cyclops appears in the 1st Block of the Theater District. It attacks with heavy, single-target Physical skills that either lower offense or Bind the party's strength, and it may use All Guard. When defeated, it may drop Cyclops Cache and Cyclops Tear. Cyclops Cache is used to create the Demon Staff for Ryuji, and the Moses Sandals for Chie. Cyclops Tear is used to create the Tonbokiri for Ken.