A pithos is a large ceramic jar used by certain ancient civilizations that bordered the Mediterranean during the Neolithic, the Bronze Age and the Iron Age. It was primarily used to store liquids, such as wine and oil, or food, such as grain. Some pithoi were also used for rituals and burials.
According to the ancient Greek poet Hesiod's Theogony,Pandora's box was originally a large jar, a pithos. The shift in object is attributed with the 16th-century humanist Erasmus of Rotterdam, who erroneously mistook the Greek pithos (storage jar) as the Greek pyxis (small box) when he translated Hesiod's original story into Latin.
In Greek mythology, Pandora's box is said to have contained all the evils of mankind, such as death and disease. Pandora, or her husband Epimetheus in some variants, opened the box and released all the evils, except for one, into the world. The one item that did not escape and remained within the box was hope which in some depictions was treated as the worst evil of all.
Sophia summons Pithos to fight Shadows alongside the protagonist. Unlike most Personas, it is adhered to Sophia from the start and is not considered being "awakened to."
However, in order to render herself immune from her misguided creator Kuon Ichinose's attempted brainwashing and reform her, Sophia receives an awakening, turning Pithos into its true form, Pandora. Pandora is awakened exactly like any other Persona (migraines, following by its user's mask breaking in severe pain) and grants Sophia newfound strength, giving her the ability to learn the rare Makougaon. The only other persona who naturally learns this skill is the post-game Persona Metatron.