Joker may refer to:
- Joker, the character from Persona 2: Innocent Sin,
- JOKER, the character from Persona 2: Eternal Punishment.
- Joker, a Persona from Persona 2: Eternal Punishment,
- Joker, a mystical ailment from Persona 2: Eternal Punishment.
- Joker, a song played by the MUSES band in the Persona 2 duology.
- Joker, the Phantom Thief codename of the protagonist of Persona 5.
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