According to Greek mythology, Io was the priestess to Hera, wife of the thunder god Zeus. Zeus took a liking on her, and to avoid detection from his jealous wife, he shrouded the place where he seduced Io with clouds. Naturally, Hera was suspicious of the cloud's formation as well as Zeus' apparent absence from Mount Olympus. When she descended, she found Zeus as a white cloud alongside a beautiful heifer. Hera knew full well that the heifer was Io, turned by Zeus, and to trap him Hera demanded Zeus the heifer as a present. Zeus had no choice but to present heifer Io to Hera, who set the multiple-eyed giant Argus Panoptes to guard her. Zeus then sent Hermes to lull Argus to sleep, and in that moment set Io free, where she roamed all the way to Egypt.
Concept anime artwork of Io in Persona 3 The Movie
Io's Persona 3 The Movie concept design
Io in battle
Io appears in Persona 3 Manga
Yukari Takeba summoning Io
Io appears in Persona 3 The Movie
Io in Side P3
Trivia
As Yukari's initial persona Io's history and actions mimic Yukari's own, both were saddled with heavy burdens inadvertently caused by their fathers, were severely punished for their fathers crimes, found themselves at a crossroads in the middle of their journeys but ultimately found it within them to continue their journeys and finally fix the problems left for them. Io also shares loose ties to Yukari's ultimate persona Isis as she found the answers she needed in Egypt the birthplace of Isis mythology.
Io's appearing with her eyes closed and bound to the heifer foreshadows Yukari's own feelings and desire to forget and look away from her past, but like Io she is still bound to her past and can never truly move on until she finds the answers she seeks.
The Zodiac sign Taurus can be seen between the nostrils of the "heifer", indicating Io's association with the constellation.
Yukari is a Libra, not Taurus. But another party member in the Persona series of the Lovers Arcana, Lisa Silverman, is indeed a Taurus.
Io appears as a palette swap for Tomoe Gozen when Chie Satonaka is using her Yukari palette.