Known as Hekatonkheires or Hecatonchires, they were giant beings from Greek myth. Having one hundred hands and fifty heads, their father Uranus found them disgusting and threw them into Tartarus. Eventually Zeus would free them and they would aid the Gods against the Titans.
Hecatonchires can be encountered as a boss by using Kymopoleia's Hair Accessory in Shinjuku. The boss has a small chance of reflecting any physical attack and will always reflect fire. Rarely, he will drop an Abyss Seed. Turning this in to the Yagiya on Suginami Tunnels' gold-level instance's final floor will give players the ability to fuse Hecatonchires. He is fused through a special triple fusion of Ubelluris, Cyclops, and Ogre.
DemiKids Light & Dark
"An awesome demon with six arms that can crush the life out of any opponent."
Known as Hekaton, he can perform the combo Megaton with Krak or Cyclops.
Devil Children Messiah Riser
Hecatoncheir appears as the boss of Wind Makai. A General of the Imperium, he hides inside his cave while his soldiers guard the switches that will force him out. Unlike most bosses he lacks a demon soldier to aid him in combat by healing or attacking foes, likely due to his high attack and defense. Upon defeat he drops the Green Crystal.
Digital Devil Saga: Avatar Tuner 2
Known as Hecatoncheires, he is fought as a boss is the second area of the game. After Serph and company climb a ladder with a small Karma Terminal near the end of the area, they will be confronted by a Karma Society Officer, who will transform into Hecatoncheires and attack.
Hecatoncheires will counter physical attacks and has access to a special attack called Hundred Fist, which gets progressively stronger as he gets weaker and hits the whole party. Multiple party members with Tera and Dia will make the battle easier. Hecatoncheires can later be encountered as a normal enemy in the corrupted EGG Installation.