Clotho is the youngest of the three Moirae Sisters, and is derived from the Greek personification of fate. Clotho spins the thread of life. Clotho was responsible for spinning the thread of human life. She also made major decisions, such as when a person was born, thus in effect controlling people's lives. This power enabled her not only to choose who was born, but also to decide when gods or mortals were to be saved or put to death.
Clotho and her sisters (Atropos and Lachesis) were the daughters of Erebus and Nyx, though later they are said to have been born of Zeus and Themis. Clotho is also mentioned in the tenth book of the Republic of Plato as the daughter of Necessity. Her Roman equivalent is Nona.
As one of the three fates her impact on Greek mythology was significant. Clotho, along with her sisters and Hermes, was given credit for creating the alphabet for their people, forced the goddess Aphrodite into making love with other beings, weakened the monster Typhon with poison fruit, persuaded Zeus to kill Asclepius with lightning, and even aided the gods in their war with the Giants by killing Agrius and Thoas with bronze clubs. Even though Clotho and her sisters were worshiped as goddesses, their representation of fate is more central to their role in mythology.
Clotho also possess her life-giving powers in the myth of Tantalus, as shown when she brought Pelops, Tantalus' son, back to life, with the exception of his eaten shoulder, which was replaced by a chunk of ivory.
Clotho acts as one of the three bosses of Nakano's silver-level Stone Site instance. By obtaining the Red Thread of Fate from the endchest, players are able to obtain her plug-in by speaking with the Suspicious Looking Man? NPC. She is a special double-fusion of Lamia and Aello.
Clotho can be encountered inside of the Tennozu Shelter, along with her sisters, Lachesis and Atropos. Clotho and Atropos can perform a combo of sorts during their attack turns. Should Clotho successfully put a party member to sleep with her Lullaby skill, Atropos can instantly kill afflicted members with her Eternal Rest skill.
Clotho can teach the Lullaby, Diarama, Recarm and Diarahan skills through her Demon Whisper. She benefits from learning healing, Fire and ailment skills.
"The youngest of the three Moirae Sisters of Greek legend. She spins the threads of life with her spindle."
—Persona 5 background
Clotho is the second Persona of the Fortune Arcana and can only be obtained through fusion in the Velvet Room. She is the first Persona to learn the Mahama, Tetraja and Energy Shower skills, second of four Personas to learn Me Patra, and the second of two Personas to learn Invigorate 1. When itemized through Electric Chair execution, Clotho yields an Invigorate 1 Skill Card.
Due to her being one of the Personas to learn the Tetraja skill, she can be used to further the StrengthConfidant with Caroline and Justine. After leveling up Clotho to level 27 so that she learns the Tetraja skill, fusing her with Regent results in the requested Lachesis with Tetraja required for Rank 7 of the Confidant.
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