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Apathy Syndrome

A victim of Apathy Syndrome in Persona -trinity soul-

"Those Apathy Syndrome rumors have been all over TV lately. Same with those cult members... How did things end up this way? Well, this is what they said about it on TV yesterday... It's a "disease" born from modern society, where the darkness in their hearts completely takes over. They say it's inevitable in a hopeless society like ours, and that its victims are victims of society."
Isako Toriumi explaining Apathy Syndrome, Persona 3

Apathy Syndrome (無気力症, Mukiryoku-shou)? is a term predominantly seen in Persona 3. It refers to a mysterious condition that reduces its victims to a vegetative state.



Persona 3[]

Apathy Syndrome is a mysterious condition that affects students of Gekkoukan High School and other residents of Tatsumi Port Island during the course of Persona 3. Those suffering from the syndrome suffer from debilitating levels of apathy. When it strikes, the inflicted will collapse in a heap where ever they happen to be and become unable to move, feed or care for themselves. The number of cases grows in correlation with the approach of the full moon, when a Shadow makes an appearance somewhere in the city. The cases quickly decrease each time a Shadow is defeated, only to slowly rise again as the next full moon approaches. People affected by the Apathy Syndrome are called "the Lost" by the inhabitants of Tatsumi Port Island.

It is later explained that Apathy Syndrome is a result of having one's psyche eaten by Shadows. Due to having their soul taken away, the victims are reduced to a vegetative state. It is implied that when a psyche is stolen, it somehow ends up with the boss Shadow that will appear during the following Full Moon (either due to that specific Shadow having eaten them itself or by the lesser Shadows eating the psyches and bringing them to the boss Shadow), because following the destruction of each Full Moon Shadow by SEES, the number of the Lost decreases dramatically. However, the Lost do not recover after the fight with Arcana Strength and Arcana Fortune, which SEES attribute to the Arcana Hanged Man becoming desperate until they discover that Shuji Ikutsuki lied to them about the operations' effect on the Dark Hour.

As it turns out, the Lost are the earliest manifestations of the Fall, an event where all of mankind will forfeit their will to live. Each Full Moon Shadow was a piece of Death (a being created by Nyx, that would later become one with its creator), and so their collection of psyches was their method of facilitating the Fall.

As the game reaches its climax, Iwatodai becomes more and more wrecked, litter and entire public structures broken down and left all over the ground. At this point, some Lost may start giving out actual dialogue, instead of their usual moans and useless pleas.

While it is implied that some Lost still exist as late as March 31st, new cases stop entirely after the Fall is prevented.

Persona 4: Dancing All Night[]

Apathy Syndrome is mentioned by Naoto that the victims lost their sense of self, unable to even speak. Also known publicly as Mass Lethargy Syndrome, it has affected a large number of people who ended up in a coma and hospitalized. Ryotaro Dojima investigated the cases and discovered that there may be a link to the syndrome patients and the cursed video. This is the product of their Shadows being removed from them, which have been taken by the ribbons into the Midnight Stage.

Persona -trinity soul-[]

Apathy Syndrome reappears in the parallel universe sequel to Persona 3. In the anime, it is shown to occur whenever a person's Persona is damaged beyond repair or forcibly removed. Apathy Syndrome afflicts Ayanagi City during the incident ten years prior where Ayane Komatsubara's repressed power exploded, causing everyone without a strong enough will to succumb to the symptoms of Apathy Syndrome.

People who are inflicted with this are reduced to a vegetative state. Later in the series, as more and more cases of this appear, strange incidents begin to occur with those afflicted by the syndrome, including being possessed by those that died or disappeared during the first incident.


Playable Male protagonist - Female protagonist - Yukari Takeba - Junpei Iori - Akihiko Sanada - Mitsuru Kirijo - Fuuka Yamagishi - Aigis - Koromaru - Ken Amada - Shinjiro Aragaki - Metis
Social Link Kenji Tomochika - Hidetoshi Odagiri - Bunkichi and Mitsuko - Kazushi Miyamoto - Chihiro Fushimi - Isako Toriumi - Keisuke Hiraga - Yuko Nishiwaki - Maiko Oohashi - Pharos - Bebe - President Tanaka - Mutatsu - Mamoru Hayase - Nozomi Suemitsu - Akinari Kamiki - Rio Iwasaki - Saori Hasegawa - Ryoji Mochizuki
Major Igor - Elizabeth - Theodore - Shuji Ikutsuki - Officer Kurosawa - Takaya Sakaki - Jin Shirato - Chidori Yoshino - Takeharu Kirijo - Kouetsu Kirijo - Eiichiro Takeba - Natsuki Moriyama - Nyx - Erebus - Margaret
Minor Maki - Kiyoshi Sakuma - Mr. Edogawa - Mr. Ekoda - Mr. Miyahara - Ms. Ounishi - Mrs. Terauchi - Kikuno Saikawa - Yuu Kimijima - Souta Aizawa - Kyouka Sayama
Cameo Yukiko Amagi - Noriko Kashiwagi - Man Drinking Alone
Port Island Gekkoukan High School - Paulownia Mall - Iwatodai Station - Port Island Station - Naganaki Shrine - Dorm - Moonlight Bridge - Velvet Room
Tartarus Blocks: Thebel - Arqa - Yabbashah - Tziah - Harabah - Adamah - Monad Depths
Abyss of Time Malebolge - Cocytus - Caina - Antenora - Ptolomea - Judecca - Empyrean
Other Kyoto - Great Seal
Albums Original Soundtrack (JP / US / FES / Portable) - Bonus CD - Burn My Dread -Reincarnation- - Spring of Birth OST - Midsummer Knight's Dream OST - Falling Down OST - Winter Of Rebirth OST - Persona 20th Anniversary All Time Best Album
Songs "Burn My Dread" - "Aria of the Soul" - "Want To Be Close" - "When the Moon Reaches for the Stars" - "Iwatodai Dorm" - "Mass Destruction" - "Color Your Night" - "Deep Breath Deep Breath" - "The Meaning of Armbands" - "Deep Mentality" - "It's Going Down Now" - "Changing Seasons" - "Current Net Price Tanaka" - "Battle Hymn of the Soul" - "Kimi no Kioku" - "P3 FES" - "Mass Destruction -P3fes version-" - "Heartful Cry" - "Brand New Days" - "Soul Phrase" - "A Way of Life" - "Time" - "Wiping All Out" - "More Than One Heart" - "Fate is In Our Hands" - "One Single Word" - "One Hand, One Heartbeat" - "One Determination" - "Sound of the Beast" - "Storm for a Butterfly" - "Light in Starless Sky" - "My Testimony" - "Self Redemption" - "Full Moon Full Life"
Terminology Persona (Initial / Prime / Ultimate) - Persona user - Shadow - Wild Card - Evoker - Attack Properties - Tactics - All-out Attack - Shuffle Time - Dark Hour - Moon Phase System - Full Moon Operations - SEES - Kirijo Group - Nanjo Group - Strega - Artificial Persona user - Suppressants - Apathy Syndrome - The Fall - Death - Who's Who - Phoenix Ranger Featherman R - Plume of Dusk
P3RE: Shift - Theurgy - Combat Characteristics
Lists Arcana - Personas (P3 - FES - P - R) - Shadows - Bosses (P3 - FES) - Skills - Items (Heart Items / Vending Machines) - Status Effects - Elizabeth's Requests - Activities - Calendar - Trophies (Portable / Reload) - Steam Profile Items - Patches and Updates
School Life Daily Life - Seasons - Social Link - Social Stats - Yen - Class - Studying - Movie Theater - Bed - Part-time Jobs - Shrine - Tanaka's Amazing Commodities - Crane Machine - Chagall Café - School Club - Cooking - Walking Koromaru - Linked Episode - Computer - Refrigerator - Gardening - Books - DVDs - Studying - Fortune Telling
Other Media
Games FES - Portable - Reload - Dancing in Moonlight
Productions The Movie - The Movie: Escape from the Dark Hour - the Weird Masquerade: -Ao no Kakusei- / -Gunjou no Meikyuu- / -Souen no Kesshou- / -Ai no Seiyaku- / -Hekikuu no Kanata e- - Persona Stalker Club - 「PERSORA AWARDS」 - PERSORA AWARDS 2 - PERSORA AWARDS 3 - Persora -The Golden Best-
Drama CDs A Certain Day of Summer - Daylight / Moonlight - Character Drama CD Vol. 1 / Vol. 2 / Vol. 3 / Vol. 4 / Vol. 5 - New Moon / Full Moon - Portable Vol. 1 / Vol. 2
Publications Manga - Shadow Cry - Memento Mori - Owari no Kakera - Alternative Heart - Velvet Blue - Persona Magazine - Dear Girls Comic Anthology - Dengeki Comic Anthology - Tartarus Theater - Persona VS - Persona 3 Reload: Beginnings
Mobile Games The Night Before - Persona Ain Soph - Social - Escape - Illust Puzzle - Broken Shadow - Aegis: The First Mission - Qix - Chaining Soul - Em
Events Music Live 2008 - Music Live 2009 - Music Tour 2010 - Music Live 2012 - Music Fes 2013 - Music Box 2014 - Super Live 2015 - Livehouse Tour 2015 - Super Live 2017 - Super Live 2019- 25th Anniversary Symphonic Concert
20th Anniversary Festival - 25th Anniversary - 25th FES
Miscellaneous Merchandise
Characters Shin Kanzato - Ryo Kanzato - Jun Kanzato - Yuki Kanzato - Haruka Kanzato - Shigeru Kanzato - Takuro Sakakiba - Megumi Kayano - Yumi Tasaka - Noboru Inui - Kunio Ito - Eiko Nikaido - Tomohiro Narasaki - Touma Shikura - Yuji Kimoto - Soutarou Senou - Saki Tachibana - Taiichi Udo - Wakasa Kusu - Shiiba Kusu - Kanaru Morimoto - Keisuke Komatsubara - Ayane Komatsubara - Akihiko Sanada - Igor
Personas AbelAditi - Astarte - Cain - Devi - Diana - Gozanze - Guukyou - Hermod - Nebuchadnezzar - Nebuzaradan - Qin Shubao - Seth - Spartacus - Utnapishtim - Yuchi Jingde
Locations Ayanagi City
Terms Persona - Persona user - Apathy Syndrome - Kagenuki - Marebito - Persona Suppressors - Reverse cases - Ayanagi Investigation Squad - Sea of Souls
Albums Original Soundtrack
Songs "Breakin' Through" - "Burning Men's Soul" - "Found Me" - "Mellow Dream" - "Reverse the Destiny" - "Somewhere" - "Soul Drive"
Concerts Music Live 2008 - Music Live 2009 - Music Tour 2010 - Music Live 2012
Archive Episodes - The Sound of Christmas - Persona Radio
Playable Rise Kujikawa - Yu Narukami - Kanami Mashita - Yosuke Hanamura - Chie Satonaka - Kanji Tatsumi - Teddie - Yukiko Amagi - Naoto Shirogane - Nanako Dojima - Margaret - Marie - Tohru Adachi - Hatsune Miku
Non-playable Protagonist - Ryotaro Dojima - Minoru Inoue - Sumomo Ujima - Tomoe Sayama - Tamami Uesugi - Nozomi Nakahara - Kyoka Ochimizu - Dance Instructor - Yuko Osada - Mikuratana-no-Kami - President Tanaka
Other Velvet Room - Yomotsu Hirasaka - Takura Productions - Inaba - Midnight Channel
Midnight Stage Kujikawa Rise (Stage) - Circus Tent - Sultry Lounge - Doll House - Romantic Castle - Mechanical Castle - Event Space - Mikuratana-no-Kami's Realm
Albums Persona 4: Dancing All Night Original Soundtrack
Songs Dance! - Calystegia
Terminology Persona - Persona User - Shadow - Kanamin Kitchen - LMB Festival - Shadow Self - Investigation Team - Apathy Syndrome
Lists Trophies